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Targeted Editing of Avian Herpesvirus Vaccine Vector using CRISPR/Cas9 Nuclease

Research Article

Herpesvirus of turkey (HVT) is an avian alphaherpesvirus used as live vaccine against Marek's disease for more than 40 years. Here, we describe the application of CRISPR/Cas9-based genome editing as a rapid and efficient method of introducing targeted mutations to the genome of a live herpesvirus vaccine vector using a transfection-infection system.

Published: 15 Nov 2016


Scope of the Journal

International Journal of Vaccines and Technologies

The Journal aims to provide readers with an easy access to all the latest advances in vaccine developments. The Journal keeps up to date with the latest finding in the field of vaccines and technology.
The Journal provides detailed information on all the latest technologies used in the production of vaccines including recent advances in vaccine technology stemming from the application of genetic engineering, effective formulations, adjuvants and routes of delivery for vaccines.
The scope of The Journal varies from latest technologies in the development of vaccines to production of vaccines in a cost effective manner.

Editorial Board


Dr. Dong Gao

Shenzhen Hornetcorn Biotechnology, China


Dr. Vasco Ariston de Carvalho Azevedo

Federal University of Minas Gerais, Brazil

Editorial Board

Dr. A. C. Matin

Stanford University School of Medicine, USA

Dr. Philip L. Kong

Fred Hutchinson Cancer Research Center, USA

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Research Topics

☛ Vaccines and Immunizations
☛ Types of Vaccines
☛ Production of Vaccines
☛ Viruses and Cancer
☛ Clinical Virology
☛ Molecular Virology
☛ Infections and Unusual infectious agents
☛ Emerging Viruses
☛ Epidemiology
☛ Developing Immunity

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International Journal of Vaccines and Technologies

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San Diego CA 92101 | USA
Phone: 1-619-471-1648
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