Conference Proceeding

Drug Discovery and Development from Horticulture Crops

Dr. B.P. Nautiyal

Horticultural crops like fruits, vegetables, spices and some of the ornamentals are richest sources of carbohydrate, fiber, vitamins, protein and bioflavonoid and largely regarded as a protective and nutritional food. Besides fulfilling nutritional requirements they also have a capacity to prevent or cure various diseases. These horticultural crops have various therapeutic values too. Fruit juices of citrus, grape and pineapple helps in preventing atherosclerosis and cancer. Vegetable like tomato, broccoli, bitter gourd are rich in antioxidant, vitamin C, carotene, glycosides, folate, potassium etc. Therefore, has powerful disease fighting properties against cancer, cardiovascular disease, diabetes and obesity. Spices i.e., ginger, turmeric, black pepper, cumin, clove, chili contains various Phytochemical and antioxidants that helps in curing various diseases. The edible flowers are enriched with various pigments viz., chlorophyll, flavonoids, xanthophylls, carotenoids, betalain, anthocyaninand also have anticancer, anti-inflammatory, antitumor, antimicrobial and antimutagenic properties. The hike in prices of these medicines and life time dependence along with their adverse effect on human body shifted keen interest of people towards the herbal based drugs and formulations.

With increasing the demand of herbal based medicine worldwide, it opened the door of unlimited possibilities and as a result pharmaceutical companies started production on massive scale. However, the unmet medical need as most of the drug are not able to cure disease completely and also the report and emergence of several new diseases i.e. BSE, AIDS, Alzheimer’s; obesity, different kind of flu, spread of JEEKA virus; low efficacy of known drugs for dementia (madness) and cancer etc.; side effects (antidepressants, antipsychotics); resistance to available antibiotics; downstream health costs (Alzheimer’s; spinal injury); cost of therapy (Viagra, Interleukins (immune deficiency); costs to individual/country; (depression); sustain industrial activity and this open an avenue to discover and develop drugs from traditionally used medicinal herbs. Horticultural crops besides many known therapeutic values are not taken up seriously for developing drugs despite huge potential. Therefore, present paper deals with medicinal values of some important horticulture crops and addresses drug discovery and development in general to open this known but greatly ignored aspect of horticulture crops.

Published: 08 November 2017


Copyright: © 2017 Dr. B.P. Nautiyal. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.